Electrophysiology dataset describing function of hERG potassium channels expressed in HEK cells

Download files
Access & Terms of Use
open access
Abstract
High-throughput patch clamp electrophysiology dataset acquired on Nanion syncropatch 384PE platform describing voltage dependent gating of hERG potassium channels expressed in HEK cells. Specific voltage protocols: 1) Steady state activation 2) Steady state deactivation 3) Onset of inactivation This example dataset accompanies the methods paper: Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology by Chai-Ann Ng, Jessica Farr, Paul Young, Monique J. Windley, Matthew D. Perry, Adam P Hill, View ORCID ProfileJamie I Vandenberg. Preprint available at : https://doi.org/10.1101/2021.02.02.427891
Link to External Data Repository
Electronic Location
Contact Information
Research Data Creator(s)
Lead Chief Investigator
Other Contributor(s)
Corporate/Industry Contributor(s)
Publication Year
2021
Resource Type
Dataset
Keyword(s)
electrophysiology
ion channel
hERG
cardiac arrhythmia
patch clamp
UNSW Faculty
Files
download Syncropatch_WThERG.zip 909.18 MB ZIP archive
Related dataset(s)
Related publication(s)
Related grant(s)
Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology