Abstract
Background and Aims:
It is increasingly recognised that major adult public health issues, related to development,
behaviour and lifestyle have their origins during pregnancy, infancy and early childhood.
The aim of this study is to utilise mixed methodology to build a conceptual framework,
theory and model describing the mechanisms by which multilevel factors influence the
developmental and life course outcomes with a focus on perinatal depression.
Methodology and Methods:
I used a critical realist approach to social epidemiology theory building. Emergent
methods included: key informant interviews, focus groups, thematic analysis, conceptual
mapping, situational analysis, factor analysis, logistic, linear, and Bayesian spatial and
multilevel regression studies. Explanatory theory building utilised abductive Inference to
the Best Explanation.
Results:
Theoretical concepts emerging included: loss of expectation, marginalisation, loss of
control, nurturing and support, social support networks, access to services, ethnic
migration and the role of global economy, business and media. Multilevel spatial studies
suggest that strong ecological social networks increase depression among migrant
mothers but not Australian mothers.
Discussion
The study found accumulating evidence that maternal stress, during and after pregnancy,
is a cause of maternal depression and altered developmental trajectory of her infant.
Emerging was the centrality of expectation lost as a possible trigger of stress and
depression. Global, economic, social and cultural mechanisms were identified that
explain maternal stress and depression within family and neighbourhood contexts. The
challenge for policy and practice is to support mothers and their partners during the
transition to parenthood.
The Thesis
In the neighbourhood spatial context, in keeping with critical realist ontology, globaleconomic,
social and cultural level generative powers trigger and condition maternal
psychological and biological level stress mechanisms resulting in the phenomenon of
maternal depression and alteration of the infants’ developmental trajectory.