Publication:
Epidemic syphilis among homosexually active men in Sydney

dc.contributor.author Jin, F en_US
dc.contributor.author Prestage, Garrett en_US
dc.contributor.author Kippax, Susan en_US
dc.contributor.author Pell, Catherine en_US
dc.contributor.author Donovan, Basil en_US
dc.contributor.author Kaldor, John en_US
dc.contributor.author Grulich, Andrew en_US
dc.date.accessioned 2021-11-25T14:59:47Z
dc.date.available 2021-11-25T14:59:47Z
dc.date.issued 2005 en_US
dc.description.abstract Objectives: To describe trends in the notification of infectious syphilis in New South Wales, the characteristics of homosexually active men recently notified with early syphilis, and the seroprevalence and incidence of syphilis, as well as associated risk factors, in a Sydney cohort of HIV-negative homosexually active men. Design, setting and participants: Secondary analysis of New South Wales infectious syphilis surveillance data from 1998 to 2003; a case series of 57 homosexually active men diagnosed with early syphilis in inner Sydney from December 2002 to January 2004; and a prospective cohort study of syphilis among 1333 HIV-negative homosexually active men in Sydney recruited from June 2001 to December 2003. Main outcome measures: Rates of notification of infectious syphilis in New South Wales and in areas of inner Sydney; behavioural and clinical features of men with syphilis in the case series; and incidence of syphilis and hazard ratios (HRs) associated with sexual behaviours in the cohort study. Results: Infectious syphilis notifications in inner Sydney rose more than 10-fold (from 6 in 1999 to 162 in 2003), and the increase was confined to men. Of 57 men with early syphilis in the case series, 54% were HIV-positive and 32% reported no symptoms of syphilis. These 57 men were highly sexually active and likely to report recreational drug use. In the cohort study, 1292 men (97% of participants) consented to syphilis testing; the incidence of syphilis was 0.78 per 100 person-years, and risk factors included reporting unprotected anal intercourse with HIV-positive partners (HR, 5.31; 95% Cl, 2.00-184.93) and insertive oral sex (HR, 4.55; 95% Cl, 1.14-18.18). Conclusion: Syphilis has been re-established among homosexually active men in Sydney, and HIV-positive men are over-represented. Frequent screening is needed in this population to curb the transmission of both syphilis and HIV. en_US
dc.identifier.uri http://hdl.handle.net/1959.4/44063
dc.language English
dc.language.iso EN en_US
dc.rights CC BY-NC-ND 3.0 en_US
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/3.0/au/ en_US
dc.source Legacy MARC en_US
dc.title Epidemic syphilis among homosexually active men in Sydney en_US
dc.type Journal Article en
dcterms.accessRights metadata only access
dspace.entity.type Publication en_US
unsw.accessRights.uri http://purl.org/coar/access_right/c_14cb
unsw.relation.faculty Medicine & Health
unsw.relation.faculty Arts Design & Architecture
unsw.relation.ispartofissue 4 en_US
unsw.relation.ispartofjournal Medical Journal of Australia en_US
unsw.relation.ispartofpagefrompageto 179-183 en_US
unsw.relation.ispartofvolume 183 en_US
unsw.relation.originalPublicationAffiliation Jin, F, National Centre in HIV Epidemiology & Clinical Research, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Prestage, Garrett, National Centre in HIV Epidemiology & Clinical Research, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Kippax, Susan, National Centre in HIV Social Research, Faculty of Arts & Social Sciences, UNSW en_US
unsw.relation.originalPublicationAffiliation Pell, Catherine en_US
unsw.relation.originalPublicationAffiliation Donovan, Basil, National Centre in HIV Epidemiology & Clinical Research, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Kaldor, John, National Centre in HIV Epidemiology & Clinical Research, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Grulich, Andrew, National Centre in HIV Epidemiology & Clinical Research, Faculty of Medicine, UNSW en_US
unsw.relation.school The Kirby Institute *
unsw.relation.school Centre for Social Research in Health *
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