Publication:
Internet cognitive behavioural treatment for mixed anxiety and depression: a randomised controlled trial and evidence of effectiveness in primary care

dc.contributor.author Newby, Jill en_US
dc.contributor.author Mackenzie, Anna en_US
dc.contributor.author Williams, Alishia en_US
dc.contributor.author McIntyre, Karen en_US
dc.contributor.author Watts, Sarah en_US
dc.contributor.author Wong, Nora en_US
dc.contributor.author Andrews, Andrews en_US
dc.date.accessioned 2021-11-25T12:26:53Z
dc.date.available 2021-11-25T12:26:53Z
dc.date.issued 2013 en_US
dc.description.abstract Background: Major Depressive Disorder (MDD) and Generalised Anxiety Disorder (GAD) have the highest comorbidity rates within the internalising disorders cluster, yet no internet-based Cognitive Behavioural Treatment (iCBT) exists for their combined treatment. Methods: We designed a 6-lesson therapist-assisted iCBT program for mixed anxiety and depression. Study 1 was a Randomised Controlled Trial (RCT) comparing the iCBT program (n=46) versus Wait-List Control (WLC, n=53) for patients diagnosed by structured clinical interview with MDD, GAD or co-morbid GAD/MDD. Primary outcome measures were the PHQ-9 (depression), GAD-7 (generalised anxiety), K-10 (distress) and WHODAS-II (disability). The iCBT group was followed-up at 3-months post-treatment. In Study 2, we investigated the adherence to, and efficacy of the same program in a primary care setting, where patients (n=136) completed the program under the supervision of primary care clinicians. Results: The RCT showed that the iCBT program was more effective than WLC, with large within- and between-groups effect sizes found (>.8). Adherence was also high (89%), and gains were maintained at 3 month-follow-up. In Study 2 in primary care, adherence to the iCBT program was low (41%), yet effect sizes were large (>.8). Thirty per cent of non-completers experienced benefit. Conclusions: Together the results show that iCBT is effective and adherence is high in research settings, but there is a problem of adherence when translated into the ‘real world.’ Future efforts need to be placed on developing improved adherence to iCBT in primary care settings. en_US
dc.identifier.issn 0033-2917 en_US
dc.identifier.uri http://hdl.handle.net/1959.4/52646
dc.language English
dc.language.iso EN en_US
dc.rights CC BY-NC-ND 3.0 en_US
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/3.0/au/ en_US
dc.source Legacy MARC en_US
dc.subject.other depression en_US
dc.subject.other cognitive behaviour therapy en_US
dc.subject.other transdiagnostic en_US
dc.subject.other anxiety en_US
dc.subject.other internet en_US
dc.subject.other effectiveness en_US
dc.subject.other treatment outcome en_US
dc.title Internet cognitive behavioural treatment for mixed anxiety and depression: a randomised controlled trial and evidence of effectiveness in primary care en_US
dc.type Journal Article en
dcterms.accessRights open access
dspace.entity.type Publication en_US
unsw.accessRights.uri https://purl.org/coar/access_right/c_abf2
unsw.description.notePublic http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8838303 en_US
unsw.description.publisherStatement This article has been accepted and published on the Cambridge University Press website as a "first view" article. It will be included in an upcoming issue of the journal Psychological Medicine. en_US
unsw.identifier.doiPublisher http://dx.doi.org/10.1017/S0033291713000111 en_US
unsw.relation.faculty Medicine & Health
unsw.relation.ispartofjournal Psychological Medicine en_US
unsw.relation.originalPublicationAffiliation Newby, Jill, Psychiatry, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Mackenzie, Anna, Psychiatry, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Williams, Alishia, Psychiatry, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation McIntyre, Karen, Psychiatry, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Watts, Sarah, Psychiatry, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Wong, Nora, Psychiatry, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Andrews , Andrews, Psychiatry, Faculty of Medicine, UNSW en_US
unsw.relation.school School of Psychiatry *
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