Chlamydia and gonorrhoea infections and the risk of adverse obstetric outcomes: a retrospective cohort study Liu, Bette en_US Roberts, Christine en_US Clarke, Marilyn en_US Jorm, Louisa en_US Hunt, Jenny en_US Ward, James en_US 2021-11-25T12:27:42Z 2021-11-25T12:27:42Z 2013 en_US
dc.description.abstract Objectives: To examine the association between prior chlamydia and gonorrhoea infections and adverse obstetric outcomes. Methods: Records of women resident in New South Wales, Australia with a singleton first birth during 1999-2008 were linked to chlamydia and gonorrhoea notifications using probabilistic linkage. Obstetric outcomes and potential confounders were ascertained from the birth record. Logistic regression, adjusted for potential confounders was used to estimate the association between a disease notification prior to the birth and adverse birth outcomes: spontaneous preterm birth (SPTB), small for gestational age (SGA) and stillbirth. Results: Among 354217 women, 1.0% (n=3658) had a prior chlamydia notification; 0.06% (n=196) had a prior gonorrhoea notification. The majority of notifications (>80%) occurred before the estimated conception date. 4.1% of women had a SPTB, 12.1% had a SGA baby and 0.6% of women had a stillbirth. Among women with a prior chlamydia notification, the risk of SPTB and stillbirth was increased, aOR 1.17 (95%CI 1.01,1.37) and aOR 1.42 (95%CI 1.02,1.99) respectively but there was no association with SGA, aOR 0.99 (95%CI 0.89,1.09). For women with gonorrhoea the risks for SPTB, stillbirth and SGA were respectively aOR 2.50 (95%CI 1.39-4.50), 2.26 (95%CI 0.55-9.26) and 0.98 (95%CI 0.57-1.67). Among women with a prior chlamydia diagnosis, the risk of SPTB did not differ between women diagnosed >1 year prior to conception, within the year prior to conception or during the pregnancy, (p=0.9). Conclusions: Sexually transmissible infections in pregnancy and the pre-conception period may be important in predicting pregnancy outcomes. en_US
dc.identifier.issn 1368-4973 en_US
dc.language English
dc.language.iso EN en_US
dc.rights CC BY-NC-ND 3.0 en_US
dc.rights.uri en_US
dc.source Legacy MARC en_US
dc.subject.other obstetrics en_US
dc.subject.other chlamydia en_US
dc.subject.other gonorrhoea en_US
dc.subject.other preterm birth en_US
dc.subject.other stillbirth en_US
dc.title Chlamydia and gonorrhoea infections and the risk of adverse obstetric outcomes: a retrospective cohort study en_US
dc.type Journal Article en
dcterms.accessRights open access
dspace.entity.type Publication en_US
unsw.identifier.doiPublisher en_US
unsw.relation.faculty Medicine & Health
unsw.relation.ispartofjournal Sexually transmitted infections en_US
unsw.relation.ispartofpagefrompageto 672-678 en_US
unsw.relation.ispartofvolume 89 en_US
unsw.relation.originalPublicationAffiliation Liu, Bette, Public Health & Community Medicine, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Roberts, Christine, University of Sydney en_US
unsw.relation.originalPublicationAffiliation Clarke, Marilyn, Grafton Base Hospital en_US
unsw.relation.originalPublicationAffiliation Jorm, Louisa, University of Western Sydney en_US
unsw.relation.originalPublicationAffiliation Hunt, Jenny, Aboriginal Health and Medical Research Council en_US
unsw.relation.originalPublicationAffiliation Ward, James, Kirby Institute, Faculty of Medicine, UNSW en_US School of Population Health * The Kirby Institute *
unsw.subject.fieldofresearchcode 111706 Epidemiology en_US
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