Serum adiponectin levels in normal and hypertensive states of pregnancy O'Sullivan, Anthony en_US Kriketos, A en_US Martin, Allison en_US Brown, Mark en_US 2021-11-25T14:26:15Z 2021-11-25T14:26:15Z 2006 en_US
dc.description.abstract Objective: The aim of this study was to quantify adiponectin levels in women with normal and hypertensive pregnancies to determine whether there is an independent association, while controlling for body fat and insulin sensitivity. Methods: A cross-sectional study was conducted in the following categories: 12 normotensive non-pregnant women, 10 normotensive, 12 gestational hypertensive, 13 essential hypertensive, and 12 preeclamptic women. All subjects underwent measurements of body fat by bio-impedance analysis and blood sampling. Results: Percentage of body fat and insulin resistance were greater in all pregnant groups compared with non-pregnant women. Adiponectin concentrations were significantly lower in women with normal pregnancies (18.6 ± 1.4 μg/mL, p = 0.02) compared with non-pregnant women (24.0 ± 1.5 μg/mL). However, adiponectin levels were not significantly different among normal pregnancy, gestational hypertension (19.0 ± 3.1 μg/mL), essential hypertension (24.0 ± 3.7 μg/mL) and pre-eclampsia (22.4 ± 2.5 μg/mL) groups. Adiponectin levels were inversely related to percent body fat and insulin resistance. When adiponectin levels were corrected for percent body fat and insulin resistance, no significant differences were seen among the study groups. Conclusions: Adiponectin levels are decreased in normal pregnancy, however this difference disappears when adiponectin levels are corrected for the pregnancy-related increases in body fat and insulin resistance. Adiponectin levels are not altered significantly in states of hypertension in pregnancy compared with normal pregnancy. en_US
dc.identifier.issn 1064-1955 en_US
dc.language English
dc.language.iso EN en_US
dc.rights CC BY-NC-ND 3.0 en_US
dc.rights.uri en_US
dc.source Legacy MARC en_US
dc.title Serum adiponectin levels in normal and hypertensive states of pregnancy en_US
dc.type Journal Article en
dcterms.accessRights open access
dspace.entity.type Publication en_US
unsw.description.publisherStatement This is an electronic version of an article published in Hypertension in Pregnancy, Volume 25, Issue 3 September 2006 , pages 193 - 203. HYPERTENSION IN PREGNANCY is available online at: en_US
unsw.identifier.doiPublisher en_US
unsw.relation.faculty Medicine & Health
unsw.relation.ispartofissue 3 en_US
unsw.relation.ispartofjournal Hypertension in Pregnancy en_US
unsw.relation.ispartofpagefrompageto 193-203 en_US
unsw.relation.ispartofvolume 25 en_US
unsw.relation.originalPublicationAffiliation O'Sullivan, Anthony, Clinical School - St George Hospital, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Kriketos, A en_US
unsw.relation.originalPublicationAffiliation Martin, Allison, National Centre in HIV Epidemiology & Clinical Research, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Brown, Mark, Clinical School - St George Hospital, Faculty of Medicine, UNSW en_US Clinical School St George Hospital * The Kirby Institute *
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
92 KB
Resource type