SURVIVAL AND DIFFERENTIATION OF SYNGENEIC BONE MARROW-DERIVED MONONUCLEAR CELLS IN RAT INTERVERTEBRAL DISCS

Download files
Access & Terms of Use
open access
Altmetric
Abstract
Intervertebral disc degeneration may cause chronic low back pain. Disc degeneration is characterized by dysfunctional cells and a decrease in extra-cellular components. Bone marrow derived mononuclear cells (MNC's) are a heterogeneous cell population which contains different stem/progenitor cells including mesenchymal stem cells. Transplantation of stem cells and other immature cell lines may provide a new approach to treat disc degeneration, however it is unclear whether transplanted cells can survive and differentiate in the non-vascularized disc tissue. The aim of the present study was to evaluate the feasibility of transplanting bone marrow derived MNC's to the intervertebral disc in a syngeneic rat model.
Persistent link to this record
Link to Publisher Version
Link to Open Access Version
Additional Link
Author(s)
Brisby, H
Wei, A-Q
Chung, S
Tao, H
Ma, D
Diwan, Ashish
Supervisor(s)
Creator(s)
Editor(s)
Translator(s)
Curator(s)
Designer(s)
Arranger(s)
Composer(s)
Recordist(s)
Conference Proceedings Editor(s)
Other Contributor(s)
Corporate/Industry Contributor(s)
Publication Year
2005
Resource Type
Conference Paper
Degree Type
UNSW Faculty
Files
download 1837-Brisby.pdf 1.82 MB Adobe Portable Document Format
Related dataset(s)