Publication:
Cold adaptation of archaeal elongation factor 2 (EF-2) proteins
Cold adaptation of archaeal elongation factor 2 (EF-2) proteins
dc.contributor.author | Thomas, Torsten | en_US |
dc.contributor.author | Cavicchioli, R | en_US |
dc.date.accessioned | 2021-11-25T13:24:14Z | |
dc.date.available | 2021-11-25T13:24:14Z | |
dc.date.issued | 2002 | en_US |
dc.description.abstract | Cell growth at low temperature is dependent on the ability of cells to perform protein synthesis. Cold adapted micro-organisms (psychrophilic or psychrotolerant) have a superior ability to perform translation at low temperature. This review addresses cold adaptation of protein synthesis in Archaea by examining what is presently known about thermal adaptation of elongation factor 2 (EF-2) proteins from Archaea. Despite the knowledge that Archaea are abundant in cold environments (e.g. the ocean), few cold adapted species have been isolated and studied. As a result this review is largely confined to comparative analyses of EF-2 proteins from psychrotolerant (Methanococcoides burtonii) and thermophilic (Methanosarcina thermophila) methanogens. A key finding from these studies is that in addition to inherent properties of the EF-2 proteins, intracellular factors (e.g. ribosomes and intracellular solutes) play a central role in thermal adaptation. | en_US |
dc.identifier.uri | http://hdl.handle.net/1959.4/39559 | |
dc.language | English | |
dc.language.iso | EN | en_US |
dc.rights | CC BY-NC-ND 3.0 | en_US |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/au/ | en_US |
dc.source | Legacy MARC | en_US |
dc.title | Cold adaptation of archaeal elongation factor 2 (EF-2) proteins | en_US |
dc.type | Journal Article | en |
dcterms.accessRights | metadata only access | |
dspace.entity.type | Publication | en_US |
unsw.accessRights.uri | http://purl.org/coar/access_right/c_14cb | |
unsw.relation.faculty | Science | |
unsw.relation.ispartofissue | 2 | en_US |
unsw.relation.ispartofjournal | Current Protein Peptide Science | en_US |
unsw.relation.ispartofpagefrompageto | 223-230 | en_US |
unsw.relation.ispartofvolume | 3 | en_US |
unsw.relation.originalPublicationAffiliation | Thomas, Torsten, Biotechnology & Biomolecular Sciences, Faculty of Science, UNSW | en_US |
unsw.relation.originalPublicationAffiliation | Cavicchioli, R | en_US |
unsw.relation.school | School of Biotechnology & Biomolecular Sciences | * |