Cold adaptation of archaeal elongation factor 2 (EF-2) proteins Thomas, Torsten en_US Cavicchioli, R en_US 2021-11-25T13:24:14Z 2021-11-25T13:24:14Z 2002 en_US
dc.description.abstract Cell growth at low temperature is dependent on the ability of cells to perform protein synthesis. Cold adapted micro-organisms (psychrophilic or psychrotolerant) have a superior ability to perform translation at low temperature. This review addresses cold adaptation of protein synthesis in Archaea by examining what is presently known about thermal adaptation of elongation factor 2 (EF-2) proteins from Archaea. Despite the knowledge that Archaea are abundant in cold environments (e.g. the ocean), few cold adapted species have been isolated and studied. As a result this review is largely confined to comparative analyses of EF-2 proteins from psychrotolerant (Methanococcoides burtonii) and thermophilic (Methanosarcina thermophila) methanogens. A key finding from these studies is that in addition to inherent properties of the EF-2 proteins, intracellular factors (e.g. ribosomes and intracellular solutes) play a central role in thermal adaptation. en_US
dc.language English
dc.language.iso EN en_US
dc.rights CC BY-NC-ND 3.0 en_US
dc.rights.uri en_US
dc.source Legacy MARC en_US
dc.title Cold adaptation of archaeal elongation factor 2 (EF-2) proteins en_US
dc.type Journal Article en
dcterms.accessRights metadata only access
dspace.entity.type Publication en_US
unsw.relation.faculty Science
unsw.relation.ispartofissue 2 en_US
unsw.relation.ispartofjournal Current Protein Peptide Science en_US
unsw.relation.ispartofpagefrompageto 223-230 en_US
unsw.relation.ispartofvolume 3 en_US
unsw.relation.originalPublicationAffiliation Thomas, Torsten, Biotechnology & Biomolecular Sciences, Faculty of Science, UNSW en_US
unsw.relation.originalPublicationAffiliation Cavicchioli, R en_US School of Biotechnology & Biomolecular Sciences *
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