Does oestrogen allow women to store fat more efficiently? A biological advantage for fertility and gestation O'Sullivan, Anthony en_US 2021-11-25T14:25:58Z 2021-11-25T14:25:58Z 2009 en_US
dc.description.abstract In normal healthy-weight humans, women have a higher percentage body fat than men, a difference that commences at puberty and continues throughout adult life, suggesting that the mechanism is related to sex steroids. The first half of pregnancy is also a stage of body fat gain in women. From an energy balance point, there is no explanation why women should be fatter than men, as the latter consume more calories proportionately. Moreover, women store fat in early pregnancy when caloric intake does not significantly change. The aim of this review is to focus on evidence supporting one mechanism that may account for these findings. That is, oestrogen reduces postprandial fatty acid oxidation leading to an increase in body fat which may account for the greater fat mass observed in women compared with men and the fat gain in early pregnancy. Therefore, female puberty and early pregnancy could be seen as states of efficient fat storage of energy in preparation for fertility, foetal development and lactation providing an obvious biological advantage. Further research into this mechanism of fat storage may provide further insights into the regulation of body fat. en_US
dc.identifier.issn 1467-7881 en_US
dc.language English
dc.language.iso EN en_US
dc.rights CC BY-NC-ND 3.0 en_US
dc.rights.uri en_US
dc.source Legacy MARC en_US
dc.title Does oestrogen allow women to store fat more efficiently? A biological advantage for fertility and gestation en_US
dc.type Journal Article en
dcterms.accessRights open access
dspace.entity.type Publication en_US
unsw.identifier.doiPublisher en_US
unsw.relation.faculty Medicine & Health
unsw.relation.ispartofjournal Obesity Reviews en_US
unsw.relation.ispartofpagefrompageto 168-177 en_US
unsw.relation.ispartofvolume 10 en_US
unsw.relation.originalPublicationAffiliation O'Sullivan, Anthony, Clinical School - St George Hospital, Faculty of Medicine, UNSW en_US Clinical School St George Hospital *
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