Publication:
Willingness to participate in HIV vaccine trials among HIV-negative gay men in Sydney, Australia

dc.contributor.author Van De Ven, Paul en_US
dc.contributor.author Mao, Limin en_US
dc.contributor.author Crawford, June en_US
dc.contributor.author Prestage, Garrett en_US
dc.contributor.author Grulich, Andrew en_US
dc.contributor.author Kaldor, John en_US
dc.contributor.author Kippax, Susan en_US
dc.date.accessioned 2021-11-25T15:00:09Z
dc.date.available 2021-11-25T15:00:09Z
dc.date.issued 2005 en_US
dc.description.abstract This study aimed to determine and describe HIV-negative gay men`s willingness to participate in HIV vaccine trials. Data were from participants who completed face-to-face interviews during the first 18 months (to the end of 2002) of recruitment into the Health in Men cohort of HIV-negative gay men in Sydney. A key outcome measure was a scale of Willingness to Participate in HIV Vaccine Trials, with scores ranging from I (unwilling) to 4 (willing). The 903 participants ranged in age from 18 to 75 years (median = 36). Mean of Willingness to Participate in HIV Vaccine Trials was 2.53 (standard deviation = 0.54), with approximately 51% of the men having a score greater than the midpoint of 2.50. A reduced linear regression model yielded four significant independent associations with Willingness to Participate in HIV Vaccine Trials: lack of tertiary education (P< 0.001), having engaged `in the previous six months` in any unprotected anal intercourse with casual or non-concordant regular partners (P < 0.001), higher self-rated likelihood of HIV infection (P < 0.01), and higher mean scores on a scale of Comfort with Participation in HIV Vaccine Trials (P < 0.001). The willingness of HIV-negative gay men at potentially higher risk for HIV to participate in HIV vaccine trials augurs well for enrolment in HIV vaccine efficacy trials. Recruitment into trials is likely to be enhanced by addressing salient concerns such as confidentiality and vaccine-induced antibody positivity. Also, it will be important to ensure that gay men are educated and fully informed about HIV vaccines and trial processes. en_US
dc.identifier.issn 0956-4624 en_US
dc.identifier.uri http://hdl.handle.net/1959.4/44069
dc.language English
dc.language.iso EN en_US
dc.rights CC BY-NC-ND 3.0 en_US
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/3.0/au/ en_US
dc.source Legacy MARC en_US
dc.subject.other gay men en_US
dc.subject.other HIV vaccine trials en_US
dc.subject.other willingness to participate en_US
dc.subject.other Australia en_US
dc.title Willingness to participate in HIV vaccine trials among HIV-negative gay men in Sydney, Australia en_US
dc.type Journal Article en
dcterms.accessRights metadata only access
dspace.entity.type Publication en_US
unsw.accessRights.uri http://purl.org/coar/access_right/c_14cb
unsw.relation.faculty Arts Design & Architecture
unsw.relation.faculty Medicine & Health
unsw.relation.ispartofissue 4 en_US
unsw.relation.ispartofjournal International Journal of STD & AIDS en_US
unsw.relation.ispartofpagefrompageto 314-317 en_US
unsw.relation.ispartofvolume 16 en_US
unsw.relation.originalPublicationAffiliation Van De Ven, Paul, National Centre in HIV Social Research, Faculty of Arts & Social Sciences, UNSW en_US
unsw.relation.originalPublicationAffiliation Mao, Limin, National Centre in HIV Social Research, Faculty of Arts & Social Sciences, UNSW en_US
unsw.relation.originalPublicationAffiliation Crawford, June, National Centre in HIV Social Research, Faculty of Arts & Social Sciences, UNSW en_US
unsw.relation.originalPublicationAffiliation Prestage, Garrett, National Centre in HIV Epidemiology & Clinical Research, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Grulich, Andrew, National Centre in HIV Epidemiology & Clinical Research, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Kaldor, John, National Centre in HIV Epidemiology & Clinical Research, Faculty of Medicine, UNSW en_US
unsw.relation.originalPublicationAffiliation Kippax, Susan, National Centre in HIV Social Research, Faculty of Arts & Social Sciences, UNSW en_US
unsw.relation.school Centre for Social Research in Health *
unsw.relation.school The Kirby Institute *
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