Publication:
Predictors of psychological distress among individuals with a strong family history of malignant melanoma
Predictors of psychological distress among individuals with a strong family history of malignant melanoma
dc.contributor.author | Kasparian, Nadine | en_US |
dc.contributor.author | Meiser, Bettina | en_US |
dc.contributor.author | Butow, P | en_US |
dc.contributor.author | Simpson, John | en_US |
dc.contributor.author | Mann, G | en_US |
dc.date.accessioned | 2021-11-25T12:58:01Z | |
dc.date.available | 2021-11-25T12:58:01Z | |
dc.date.issued | 2008 | en_US |
dc.description.abstract | Despite rapid advancements in molecular genetics research, little is known about the psychological experiences of individuals with a family history of melanoma. The present study aimed to identify factors contributing to psychological distress among affected and unaffected individuals with a strong family history of melanoma. A total of 121 adults who had recently been informed of the identification of a family-specific mutation in the CDKN2A melanoma susceptibility gene, completed a self-report questionnaire assessing cancer-specific and generalized distress, and a variety of potential predictors. Having a personal history of melanoma (OR = 3.37, p = 0.033), perceiving greater family implications of melanoma (OR = 2.52, p < 0.0001), and the tendency to monitor for threatening information (OR = 3.12, p = 0.008) were associated with melanoma-specific distress. Being childless (beta = 2.09, p = 0.007), perceiving sun exposure as an important cause of melanoma (beta = 1.15, p = 0.015), and perceiving greater family implications of melanoma (beta = 1.02, p = 0.002) were associated with greater generalized anxiety, while monitoring moderated the relationship between endorsement of a genetic model of melanoma and generalized anxiety (p = 0.005). As in other common familial cancers, distress was relatively uncommon in this familial melanoma cohort, even after notification of the presence of a family mutation. Participants do not contemplate their melanoma risk in isolation, but evaluate their risk vis-a-vis the experiences of their relatives. | en_US |
dc.identifier.issn | 0009-9163 | en_US |
dc.identifier.uri | http://hdl.handle.net/1959.4/38797 | |
dc.language | English | |
dc.language.iso | EN | en_US |
dc.rights | CC BY-NC-ND 3.0 | en_US |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/au/ | en_US |
dc.source | Legacy MARC | en_US |
dc.title | Predictors of psychological distress among individuals with a strong family history of malignant melanoma | en_US |
dc.type | Journal Article | en |
dcterms.accessRights | metadata only access | |
dspace.entity.type | Publication | en_US |
unsw.accessRights.uri | http://purl.org/coar/access_right/c_14cb | |
unsw.identifier.doiPublisher | http://dx.doi.org/10.1111/j.1399-0004.2007.00949.x | en_US |
unsw.relation.faculty | Medicine & Health | |
unsw.relation.faculty | Engineering | |
unsw.relation.ispartofissue | 2 | en_US |
unsw.relation.ispartofjournal | Clinical Genetics | en_US |
unsw.relation.ispartofpagefrompageto | 121-131 | en_US |
unsw.relation.ispartofvolume | 73 | en_US |
unsw.relation.originalPublicationAffiliation | Kasparian, Nadine, Prince of Wales Clinical School, Faculty of Medicine, UNSW | en_US |
unsw.relation.originalPublicationAffiliation | Meiser, Bettina, Prince of Wales Clinical School, Faculty of Medicine, UNSW | en_US |
unsw.relation.originalPublicationAffiliation | Butow, P | en_US |
unsw.relation.originalPublicationAffiliation | Simpson, John, Computer Science & Engineering, Faculty of Engineering, UNSW | en_US |
unsw.relation.originalPublicationAffiliation | Mann, G | en_US |
unsw.relation.school | Clinical School Prince of Wales Hospital | * |
unsw.relation.school | School of Computer Science and Engineering | * |