Inheritance of a cancer-associated MLH1 germ-line epimutation

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Abstract
Persons who have hypermethylation of one allele of MLH1 in somatic cells throughout the body (a germ-line epimutation) have a predisposition for the development of cancer in a pattern typical of hereditary nonpolyposis colorectal cancer. By studying the f
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Author(s)
Hitchins, Megan P.
;
Wong, Justin J.L.
;
Suthers, Graeme
;
Suter, Catherine M.
;
Martin, David I.K.
;
Hawkins, Nicholas
;
Ward, Robyn L.
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Publication Year
2007
Resource Type
Journal Article
Degree Type
UNSW Faculty