Publication:
Genotoxicity and Transmission Electron Microscopy of Molybdocene Dichloride

dc.contributor.author Dillon, Carolyn en_US
dc.contributor.author Harding, Margaret en_US
dc.contributor.author Campbell, Kate en_US
dc.contributor.author Foster, Amalanie en_US
dc.date.accessioned 2021-11-25T13:30:37Z
dc.date.available 2021-11-25T13:30:37Z
dc.date.issued 2006 en_US
dc.description.abstract The cytotoxic effects of molybdocene dichloride (Cp2MoCl2) were investigated in V79 Chinese hamster lung cells using the micronucleus assay. Cp2MoCl2 produced significant genotoxic damage whereby 0.2 micronuclei/1000 binucleated cells were induced per μM of Cp2MoCl2. Transmission electron microscopic analysis of thin-sectioned cells treated with Cp2MoCl2 (300 μM) showed distinct morphological alterations of the nuclei, condensation of chromatin, and a high incidence of polynucleated cells. Implications for the mechanism of antitumor action of molybdocene dichloride are discussed. en_US
dc.identifier.issn 0162-0134 en_US
dc.identifier.uri http://hdl.handle.net/1959.4/39838
dc.language English
dc.language.iso EN en_US
dc.rights CC BY-NC-ND 3.0 en_US
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/3.0/au/ en_US
dc.source Legacy MARC en_US
dc.title Genotoxicity and Transmission Electron Microscopy of Molybdocene Dichloride en_US
dc.type Journal Article en
dcterms.accessRights metadata only access
dspace.entity.type Publication en_US
unsw.accessRights.uri http://purl.org/coar/access_right/c_14cb
unsw.identifier.doiPublisher http://dx.doi.org/10.1016/j.jinorgbio.2006.01.034 en_US
unsw.relation.faculty Science
unsw.relation.ispartofjournal Journal of Inorganic Biochemistry en_US
unsw.relation.ispartofpagefrompageto 1194-1198 en_US
unsw.relation.ispartofvolume 100 en_US
unsw.relation.originalPublicationAffiliation Dillon, Carolyn en_US
unsw.relation.originalPublicationAffiliation Harding, Margaret, Chemistry, Faculty of Science, UNSW en_US
unsw.relation.originalPublicationAffiliation Campbell, Kate en_US
unsw.relation.originalPublicationAffiliation Foster, Amalanie en_US
unsw.relation.school School of Chemistry *
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