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(2006)ThesisSuccessful implementation of any technology requires acceptance by the users. Numerous studies in the area of information technology acceptance, based on wellknown theories have been conducted to examine technology acceptance models and predict user adoption/acceptance behaviour. There are several studies dealing with patients’ acceptance of different telemedicine applications, but few about the patients’ acceptance of home telecare. Most existing studies are not based on a strong theoretical framework. In this study, based on an extensive literature review and preliminary qualitative data, a theoretical model of the effect of Home Telecare Management System (HTMS) characteristics and psychological variables associated with technophobia on patients’ acceptance of HTMS is proposed. The proposed model is an augmented Technology Acceptance Model (TAM) of Davis (1986), which is called Home Telecare Management System acceptance model (HTMS-AM), in which TAM has been augmented by two constructs: HTMS anxiety and HTMS self-efficacy. The model is proposed to improve our understanding regarding patients’ acceptance of HTMS, which may lead to successful design and implementation of home telecare systems. In addition, it can be used as a theoretical basis to evaluate new generations of HTMS in terms of users acceptance in the early stage of their design and development even prior to implementation. In order to test the reliability and validity of the measures, video demonstrations of a home telecare system and demonstration of a system prototype to potential users was employed. To propose the HTMS-AM the following five stages were taken: 1. General well-known theoretical models of human behaviour from psychology and technology acceptance models from information technology were reviewed to create a basic template for the proposed model. 2. A preliminary study (focus group interviews, Chapter 5) was conducted to assess patients’ perceptions of HTMS. 3. Based on an extensive literature review and findings from preliminary qualitative studies, HTMS acceptance model was proposed, to improve our understanding about factors, which may affect patients’ intention to use HTMS. Several adaptations were applied in the model to be applicable in the HTMS context, such as augmenting the model with HTMS self-efficacy and HTMS anxiety constructs. 4. To measure the different psychological variables in the proposed model, valid and reliable measures from previous studies were used. However the preliminary study was used to develop measures, which did not exist in the literature. 5. These measures were tested in the final study. The subjects were patients who had been affected with Congestive Heart Failure (CHF) and/or Chronic Obstructive Lung Disease (COPD). Given the chronic nature of these diseases, the necessity for extended monitoring and management and frequent admission to hospitals due to worsening health status, these patients were deemed the most appropriate candidates for the HTMS. Further studies with more cases need to be conducted to test the actual model in which the impact of HTMS characteristics, psychological and demographic factors associated with technophobia upon intention to use the HTMS and the correlation of these factors with each other in appropriate healthcare settings.