This dataset is for a study that aims to determine the feasibility of a double-blinded randomised, placebo-controlled study in determining the effectiveness of antibiotic prophylaxis in preventing postoperative infections in elective non-hysterectomy laparoscopic procedures for benign gynaecological conditions. Participants were randomly allocated into one of two groups - receiving 2g cephazolin and placebo (10mL normal saline) preoperatively. Data was collected pre-, intra- and post-operatively, including follow-up data collected at 2- and 6-weeks postoperatively. Primary outcomes analaysed include feasibility of a large-scales study and postoperative infection rates in both group. Secondary outcomes analysed include length of hospital stay, re-admission to hospital, unscheduled presentations to healthcare facilities and antibiotic-related reactions. It contains de-identified patient data including demographics, pre-, intra- and post-operative data, as well as follow-up data at 2-weeks and 6-weeks. Patients who have been withdrawn after randomisation are highlighted in yellow.