Dataset:
Effect of ion transport and carbonic anhydrase inhibition on parotid salivary

ac.person.position Staff
dc.coverage.spatial Australia en_US
dc.date.accessioned 2021-11-26T09:25:26Z
dc.date.available 2021-11-26T09:25:26Z
dc.date.issued 2020 en_US
dc.description.abstract In kangaroos, parotid gland secretion has >90% dependence on carbonic anhydrase activity whereas the mandibular gland secretion has >90% dependence on transport of chloride by the triple symport. Unlike kangaroos, parotid salivary [bicarbonate] in wombats is essentially constant over the whole flow range and exceeds [chloride] except at peak flow. Consequently, saliva formation by the wombat parotid gland could be initiated by acinar HCO3 secretion as in the kangaroo parotid followed by substantial ductal exchange of HCO3 for Cl or by Cl transport using the Na-K-2Cl cotransporter and/or the coupled antiports (Na/H and Cl/ HCO3) as in eutherian salivary glands. This study uses blockers of the Na-K-2Cl symport , the Cl/ HCO3 antiport, the Na/H antiport and carbonic anhydrase activity to assess the contribution of the above mechanisms to parotid saliva formation in wombats en_US
dc.identifier.uri http://hdl.handle.net/1959.4/resource/collection/resdatac_1019/1
dc.language English
dc.language.iso EN en_US
dc.rights CC-BY
dc.rights.uri https://creativecommons.org/licenses/by/4.0/ en_US
dc.title Effect of ion transport and carbonic anhydrase inhibition on parotid salivary en_US
dc.type Dataset en_US
dcterms.accessRights open access
dspace.entity.type Dataset en_US
unsw.accessRights.uri https://purl.org/coar/access_right/c_abf2
unsw.contributor.leadChiefInvestigator Beal, Alan
unsw.contributor.researchDataCreator Beal, Alan en_US
unsw.description.storageplace School of Biological, Earth & Environmental Sciences, Science Faculty, UNSW en_US
unsw.identifier.doi https://doi.org/10.26190/5e9fa4255e92e en_US
unsw.relation.OriginalPublicationAffiliation Beal, Alan, Biological| Earth & Env Sci, Faculty of Science, en_US
unsw.relation.faculty Science
unsw.relation.fundingAgency AUSTRALIAN RESEARCH COUNCIL - SMALL GRANTS
unsw.relation.fundingScheme SMALL GRANTS
unsw.relation.projectEndDate 2009-09-04
unsw.relation.projectStartDate 1995-01-01
unsw.relation.projectTitle secretion mechanisms in salivary glands of diprotodont marsupials en_US
unsw.relation.school School of Biological, Earth & Environmental Sciences
unsw.relation.unswGrantNo L19950034
unsw.subject.SEOcode 970106 Expanding Knowledge in the Biological Sciences en_US
unsw.subject.fieldofresearchcode 0606 Physiology en_US
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