Dataset:
Long-term health outcomes among CNS HAND Study cohort
Long-term health outcomes among CNS HAND Study cohort
dc.coverage.spatial | Sydney, Australia | |
dc.date.accessioned | 2022-06-20T23:22:06Z | |
dc.date.available | 2022-06-20T23:22:06Z | |
dc.date.issued | 2022-06-22 | |
dc.date.submitted | 2022-06-20T08:21:33Z | |
dc.description.abstract | The CNS HAND study was primarily conducted among 254 people living with HIV (PLHIV) and 72 HIV-negative persons from a primary care clinic in Sydney, Australia named Holdsworth House General Practice to assess the burden of HIV-associated neurocognitive disorder (HAND) among PLHIV and to validate the CogState computerized cognitive screening tool for the diagnosis of HAND. This baseline study took place between October 2011 and October 2012. Exclusion criteria at the entry of the study was alcohol or substance intoxication. Providing that majority of the study participants continue receiving care at the clinic, their long-term health outcome data on age-related non-AIDS conditions (major neurological and cognitive disorders, cardiovascular diseases, diabetes, osteoporosis, non-AIDS cancers, and chronic kidney, liver and lung diseases) were collected in June 2021 censoring the study end point at the end of April 2021. Three HIV-negative participants were excluded from this long-term outcome study because of seroconversion during the study follow-up period. This deidentified individual participant dataset was used for survival analyses to identify if PLHIV despite under suppressive combination antiretroviral therapy has higher risks for age-related non-AIDS conditions compared to age and lifestyle-matched HIV-negative persons. | |
dc.identifier.uri | http://hdl.handle.net/1959.4/100417 | |
dc.language | English | |
dc.language.iso | en | |
dc.rights | CC-BY-NC-SA | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-sa/4.0/ | |
dc.subject.other | HIV | |
dc.subject.other | Aging | |
dc.subject.other | CVD | |
dc.subject.other | Congitive disorder | |
dc.subject.other | Diabetes | |
dc.subject.other | Osteoporosis | |
dc.subject.other | Cancer | |
dc.subject.other | Survival analysis | |
dc.title | Long-term health outcomes among CNS HAND Study cohort | |
dc.type | Dataset | |
dcterms.accessRights | open access | |
dcterms.accrualMethod | Baseline data was collected between October 2010 and October 2011. Follow-up outcome data on age-related non-AIDS conditions was collected from the study entry until April the 30th 2021. CogState computerized screening tool was used for the cognitive assessment at baseline. In addition, participants’ demographics, medical history, mood status, alcohol and drug use disorders, and functional status were assessed through interviews and self-reported questionnaire at the baseline. This published dataset is formatted in wide form with each row representing a unique participant covering both baseline and follow-up visits. | |
dcterms.rightsHolder | UNSW | |
dspace.entity.type | Dataset | |
unsw.accessRights.uri | https://purl.org/coar/access_right/c_abf2 | |
unsw.contributor.researchDataCreator | Aung, Htein Linn | |
unsw.contributor.researchDataCreator | Cysique, Lucette | |
unsw.contributor.researchDataCreator | Bloch, Mark | |
unsw.coverage.temporalFrom | 2010-10 | |
unsw.coverage.temporalTo | 2021-04 | |
unsw.date.workflow | 2022-06-20 | |
unsw.identifier.doi | https://doi.org/10.26190/unsworks/24124 | |
unsw.isPublicationRelatedToDataset | Cognitive aging in people living with HIV: concept development and empirical evidence from several longitudinal cohorts in Australia and beyond | |
unsw.relation.faculty | Science | |
unsw.relation.faculty | Medicine & Health | |
unsw.relation.school | School of Psychology | |
unsw.relation.school | The Kirby Institute | |
unsw.relation.school | Clinical School St Vincents Hospital | |
unsw.subject.fieldofresearchcode | 320211 Infectious diseases | |
unsw.subject.fieldofresearchcode | 4202 Epidemiology |