Dataset:
Long-term health outcomes among CNS HAND Study cohort

dc.coverage.spatial Sydney, Australia
dc.date.accessioned 2022-06-20T23:22:06Z
dc.date.available 2022-06-20T23:22:06Z
dc.date.issued 2022-06-22
dc.date.submitted 2022-06-20T08:21:33Z
dc.description.abstract The CNS HAND study was primarily conducted among 254 people living with HIV (PLHIV) and 72 HIV-negative persons from a primary care clinic in Sydney, Australia named Holdsworth House General Practice to assess the burden of HIV-associated neurocognitive disorder (HAND) among PLHIV and to validate the CogState computerized cognitive screening tool for the diagnosis of HAND. This baseline study took place between October 2011 and October 2012. Exclusion criteria at the entry of the study was alcohol or substance intoxication. Providing that majority of the study participants continue receiving care at the clinic, their long-term health outcome data on age-related non-AIDS conditions (major neurological and cognitive disorders, cardiovascular diseases, diabetes, osteoporosis, non-AIDS cancers, and chronic kidney, liver and lung diseases) were collected in June 2021 censoring the study end point at the end of April 2021. Three HIV-negative participants were excluded from this long-term outcome study because of seroconversion during the study follow-up period. This deidentified individual participant dataset was used for survival analyses to identify if PLHIV despite under suppressive combination antiretroviral therapy has higher risks for age-related non-AIDS conditions compared to age and lifestyle-matched HIV-negative persons.
dc.identifier.uri http://hdl.handle.net/1959.4/100417
dc.language English
dc.language.iso en
dc.rights CC-BY-NC-SA
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subject.other HIV
dc.subject.other Aging
dc.subject.other CVD
dc.subject.other Congitive disorder
dc.subject.other Diabetes
dc.subject.other Osteoporosis
dc.subject.other Cancer
dc.subject.other Survival analysis
dc.title Long-term health outcomes among CNS HAND Study cohort
dc.type Dataset
dcterms.accessRights open access
dcterms.accrualMethod Baseline data was collected between October 2010 and October 2011. Follow-up outcome data on age-related non-AIDS conditions was collected from the study entry until April the 30th 2021. CogState computerized screening tool was used for the cognitive assessment at baseline. In addition, participants’ demographics, medical history, mood status, alcohol and drug use disorders, and functional status were assessed through interviews and self-reported questionnaire at the baseline. This published dataset is formatted in wide form with each row representing a unique participant covering both baseline and follow-up visits.
dcterms.rightsHolder UNSW
dspace.entity.type Dataset
unsw.accessRights.uri https://purl.org/coar/access_right/c_abf2
unsw.contributor.researchDataCreator Aung, Htein Linn
unsw.contributor.researchDataCreator Cysique, Lucette
unsw.contributor.researchDataCreator Bloch, Mark
unsw.coverage.temporalFrom 2010-10
unsw.coverage.temporalTo 2021-04
unsw.date.workflow 2022-06-20
unsw.identifier.doi https://doi.org/10.26190/unsworks/24124
unsw.isPublicationRelatedToDataset Cognitive aging in people living with HIV: concept development and empirical evidence from several longitudinal cohorts in Australia and beyond
unsw.relation.faculty Science
unsw.relation.faculty Medicine & Health
unsw.relation.school School of Psychology
unsw.relation.school The Kirby Institute
unsw.relation.school Clinical School St Vincents Hospital
unsw.subject.fieldofresearchcode 320211 Infectious diseases
unsw.subject.fieldofresearchcode 4202 Epidemiology
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